Multiple myeloma is a cancer that develops in a type of white blood cell called a plasma cell. Healthy plasma cells help fight infection by making proteins called antibodies. Antibodies find and attack germs. In multiple myeloma, cancerous plasma cells form in the bone marrow. Bone marrow is the soft substance inside bones where blood…
Evolution of Multiple Myeloma Treatment: A Historical Perspective Multiple myeloma treatment has progressed substantially, translating into improved patient outcomes. Prior to the mid-20th century, myeloma was rapidly fatal with limited therapeutic options beyond palliative radiotherapy. The 1960s brought alkylating agents and steroids extending survival to 2-3 years. Addition of high-dose chemotherapy and stem cell transplantation…
